TENVIR EM

DESCRIPTION

  • Composition : Tenofovir Disoproxil Fumarate and Emtricitabine
  • Manufacturer: Cipla
  • Indication : Anti HIV
  • Packaging : Bottle
  • Dosage Form : Tablet

PACKAGE

  • 300mg/200mg
Category:

Brand Name: Tenvir EM
Generic Name: Emtricitabine and Tenofovir Disoproxil Fumarate
Manufacturer: Cipla
Dosage Form: Tablet
Strength:200mg/300mg
Composition: Emtricitabine (200mg) and Tenofovir Disoproxil Fumarate (300mg)
Indication: HIV
Storage: Store at room temperature

Overview
Tenvir EM (Emtricitabine and Tenofovir Disoproxil Fumarate) tablet is an antiretroviral medication. It is used for the treatment of infection caused by HIV (human immunodeficiency virus). This medication helps to delay the production of HIV infection and improves the quality of life. Tenvir EM tablet boost your immune system to fight against infection and prevents the virus from multiplying. It increases the CD4 cell (white blood cells that protect against infection) count in your blood. Do not take this medicine in the wrong way as it may lead to some serious side effects. If you experience any symptoms while receiving this medicine, inform your doctor immediately.

Pharmacodynamics
Emtricitabine (Tenvir EM):- a synthetic nucleoside analog of cytidine, is phosphorylated by cellular enzymes to form emtricitabine 5′-triphosphate. It inhibits the activity of the HIV-1 reverse transcriptase (RT) by competing with the natural substrate deoxycytidine 5′-triphosphate and by being incorporated into nascent viral DNA which results in chain termination. Emtricitabine is a weak inhibitor of mammalian DNA polymerase alpha, beta, epsilon, and mitochondrial DNA polymerase gamma.

Tenofovir Disoproxil Fumarate (Tenvir EM):- Tenofovir disoproxil fumarate is an acyclic nucleoside phosphonate diester analog of adenosine monophosphate. Tenofovir disoproxil fumarate requires initial diester hydrolysis for conversion to tenofovir and subsequent phosphorylations by cellular enzymes to form tenofovir diphosphate. Tenofovir disoproxil fumarate inhibits the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination. It is a weak inhibitor of mammalian DNA polymerases alpha, beta, and mitochondrial DNA polymerase gamma.

Usage
Tenvir EM tablet is a combination of two anti-HIV medicines: Emtricitabine and Tenofovir disoproxil fumarate. This medication is not a permanent cure for HIV infection. It only prevents the multiplication of HIV (human immunodeficiency virus) infection in human cells. It is important to take Tenvir EM tablet as prescribed by your doctor. It is advised not to change your regular dosing schedule without taking suggestions from your doctor. The recommended dose of Tenvir EM medicine is decided by a doctor according to your previous medical condition and response to the treatment.

Interactions
Tenvir EM tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.

Medicine Interactions
Leflunomide

Cisplatin

Tobramycin

Gentamicin

Methotrexate

Efavirenz

Disease Interactions
Renal dysfunction

Hepatic Impairment

Alcohol Interaction
Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.

Contraindication
Do not take this medicine if you are allergic to Emtricitabine and Tenofovir disoproxil fumarate.

Tenvir EM tablet is not recommended in patients known to be hypersensitive.

This medicine is not recommended for use in patients with severe kidney disease.

Substitutes
Emfovir
Tenof EM

Ricovir EM

Tofocom

Tavin EM

Side Effects
This medicine may cause some common side effects. Discuss the risks and benefits of the Tenvir EM tablets with the doctor before starting the treatment.

Common Side Effects
Trouble sleeping

Loss of strength

Fatigue

Sore throat

Swollen lymph nodes

Loss of appetite

Seizures

Cough

Unusual weakness

Blurred vision

Loss of weight

Nausea

Insomnia

Diarrhea

Blood in urine

Irregular heartbeat

Abnormal dream

Confusion

Indigestion

Constipation

Redness of skin

Taste changes

Unusual tiredness

Fever

Chills

Note – immediately contact your health care provider if any side effects occur.

Dosage
Take this medicine as prescribed by your doctor. Make sure to not skip or stop your regular dosing schedule.

Missed Dose
It is advisable not to miss a dose. If you miss a scheduled dose of Tenvir EM tablets, contact your doctor immediately.

Overdose
In case of an overdose of Tenvir EM tablets, the doctor will provide emergency medical treatment.

Warning
Before starting treatment with Tenvir EM medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.

Contraception

Use suitable methods of contraception to prevent pregnancy while taking Tenvir EM medicine.

Children and adolescents

Tenvir EM tablets are not recommended for use in children under the age of 12.

Warnings For Female
Pregnancy

Do not use Tenvir EM medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.

Breastfeeding

This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with Tenvir EM (Emtricitabine and Tenofovir Disoproxil Fumarate).

Precautions
Tenvir EM increases the risk of lactic acidosis.

Inform your doctor if you experience any side effects like- nausea, insomnia, fever, sore throat, headache, abnormal dream, anxiety, etc.

This medication may increase the risk of immune reconstitution syndrome.

Close monitoring of bone mineral density is required during treatment with this medicine.

Tenvir EM tablet is not recommended for use in patients requiring hemodialysis.

Cautions
Do not drive or operate heavy machinery.

Do not crush or break the tablet.

Not safe for pregnant women.

Do not breastfeed while receiving this medication.

DESCRIPTION

  • Composition : Tenofovir Disoproxil Fumarate and Emtricitabine
  • Manufacturer: Cipla
  • Indication : Anti HIV
  • Packaging : Bottle
  • Dosage Form : Tablet

PACKAGE

  • 300mg/200mg
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