TENOLAM

Brand name – Tenolam
Generic name – Lamivudine/Tenofovir Disoproxil Fumarate
Manufacturer – Hetero Drugs Ltd
Strength – 300 mg/300 mg
Dosage – Tablet (Oral administration)
Packaging – Bottle
Indication – HIV infection
Prescription needed – Yes

Description
Tenolam (Lamivudine/Tenofovir Disoproxil Fumarate) tablet is a prescription medicine. It is used in the treatment of HIV (Human Immunodeficiency Virus) infection. It boosts up the immunity to fight against the virus and manage AIDS (Acquired Immunodeficiency Syndrome). It slows the growth of the virus in the body and reduces HIV-related symptoms, thereby improving the lifespan of individuals. It increases the CD4 cell (white blood cells that protect against infection) count in the blood. This medicine is available at the best price in India.

Pharmacodynamics
Lamivudine:- A nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and Hepatitis B (HBV) to disrupt viral DNA synthesis. Lamivudine can form active metabolites when phosphorylated, that compete for incorporation into viral DNA. Via DNA incorporation, lamivudine metabolites inhibit the activity of the HIV reverse transcriptase enzyme and then act as a chain terminator of DNA synthesis.

Tenofovir Disoproxil Fumarate:- An acyclic nucleoside phosphonate diester analog of adenosine monophosphate. inhibits the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA-chain termination.

Usage Of Medicine
Tenolam (Lamivudine/Tenofovir Disoproxil Fumarate) tablet is a combination of two antiretroviral agents namely Lamivudine and Tenofovir Disoproxil Fumarate. This medicine is available in the strength of 300 mg/300 mg in the form of tablets for oral administration. It may be prescribed with other medications to treat HIV. It is important to take this medicine regularly at the right time for better efficacy. Also, it is advisable to not miss a dose. Make sure to report the side effects to the doctor (if any).

Interactions
Medicine interactions should be discussed with the healthcare provider before taking the Tenolam (Lamivudine/Tenofovir Disoproxil Fumarate) tablet.

Interaction With Alcohol
Interaction with Alcohol is unknown. Please consult your healthcare provider before consumption.

Interaction With Medicine
Aspirin

Tobramycin

Efavirenz

Cisplatin

Gentamicin

Methotrexate

Disease Interaction
Hepatic impairment

Renal Dysfunction

Contraindications
Allergy – Tenolam (Lamivudine/Tenofovir Disoproxil Fumarate) tablet is not indicated for use in patients with a known allergy to Tenofovir, Lamivudine, or any other ingredient of this medicine.

Severe renal impairment – Tenolam (Lamivudine/Tenofovir Disoproxil Fumarate) tablet is not indicated for use in patients with severe renal impairment.
Alternate Brands
Virofovir

Ricovir L

Forstavir L

Tavin L

Tenvir L