TRIUMEQ

Brand Name: Triumeq
Generic Name: Abacavir + Dolutegravir + Lamivudine
Manufacturer: ViiV healthcare
Dosage Form: Tablet
Strength: 600mg/50mg/300mg
Composition: Abacavir (600 mg) + Dolutegravir (50 mg) + Lamivudine (300 mg)
Indication: HIV
Packaging: 30 tablet
Storage: Store at room temperature

Overview
Triumeq tablet is a combination of three anti-HIV medicines: Abacavir, Dolutegravir, and Lamivudine. It is used for the treatment of HIV (human immunodeficiency virus) infection. This medication is not a permanent cure for HIV infection. Triumeq only prevents the multiplication of HIV (human immunodeficiency virus) infection in human cells. It is advised not to change your regular dosing schedule without taking suggestions from your doctor. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately.

Pharmacodynamics
Abacavir (Triumeq):- is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). It is phosphorylated to active metabolites that compete for incorporation into viral DNA. They work to inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis.

Dolutegravir (Triumeq):- is an HIV-1 antiviral agent. It works to inhibit HIV integrase and binds to the active site. It blocks the strand transfer step of retroviral DNA integration in the host cell. During the clinical trials, it was indicated that Dolutegravir has a tight binding and longer dissociative half-life.

Lamivudine (Triumeq):- A nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and Hepatitis B (HBV) to disrupt viral DNA synthesis. Lamivudine can form active metabolites when phosphorylated, that compete for incorporation into viral DNA. Via DNA incorporation, lamivudine metabolites inhibit the activity of the HIV reverse transcriptase enzyme and then act as a chain terminator of DNA synthesis.

Usage
Triumeq (Abacavir + Dolutegravir + Lamivudine) tablet is a combination of three antiretroviral medications. It is used for the treatment of HIV (human immunodeficiency virus) infection. boosts your immune system to fight against infection and helps to reduce the amount of HIV in your body and improves the quality of life. It is important to take Triumeq tablet as prescribed by your doctor. Do not take this medicine in the wrong way as it may lead to some serious side effects. The recommended dose of Triumeq medication is decided by a doctor according to your previous medical condition and response to the treatment.

Interactions
Triumeq tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.

Medicine Interactions
Apalutamide

Carbamazepine

Emtricitabine

Kaolin

Leflunomide

Primidone

Disease Interactions
Pancreatitis

Hepatoxicity

Renal dysfunction

Alcohol Interaction
Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.

Contraindication
Do not use this medicine if you are allergic to Abacavir, Dolutegravir, and Lamivudine

Triumeq tablet is not recommended in patients known to be hypersensitive.