LOPIKAST

DESCRIPTION

  • Composition : Lopinavir & Ritonavir
  • Manufacturer: Aprazer Healthcare
  • Dosage Form: Tablet

PACKAGE

  • 200 mg
Category:

Brand name: Lopikast

Generic name: Lopinavir and Ritonavir

Strength: 200 mg/50 mg

Manufacturer: Aprazer Healthcare

Dosage form: Tablets

Indication: HIV and AIDS

Storage: Store at room temperature.

Overview
Lopikast is an anti-HIV drug that is used in the treatment of patients with Human Immunodeficiency Virus Infection. This medication is also prescribed to relieve the symptoms and severity of Acquired Immunodeficiency Syndrome (AIDS). It comprises two antiretroviral formulations namely Lopinavir and Ritonavir. The regimen is available in the form of tablets for oral administration with a fixed strength of 200 mg/50 mg. Lopikast works by interfering with the protease and stops the production of new viruses in the body.

Pharmacodynamics
Lopinavir (Lopikast): The HIV life cycle is divided into three stages: assembly, which involves the production and packaging of essential viral components; budding, which occurs when the viral particle crosses the plasma membrane of the host cell and forms a lipid envelope; and maturation, which occurs when the viral particle changes its structure and becomes infectious. This compound hinders the cycle.

Ritonavir (Lopikast): Ritonavir is a protease inhibitor having efficacy against Human Immunodeficiency Virus Type 1 (HIV-1) (HIV-1). Protease inhibitors block the portion of HIV termed protease. HIV-1 protease is a proteolytic enzyme that converts viral polyprotein precursors into individual functional proteins seen in infectious HIV-1.

Interactions
Lopikast (Lopinavir/Ritonavir) tablets are known to interact with the following. Make sure to read and discuss the possibility with your doctor.

With Medicines
Azithromycin

Glycerol

Phenytoin Sodium

Valproate Sodium

With Diseases
Hemophilia

Hyperlipidemia

Heart block

Hepatotoxicity

Hyperglycemia

With Alcohol
Lopikast (Lopinavir/Ritonavir) can interact with alcohol and related drinks. This may cause severe effects. However, limited studies are available to justify this.

Contraindications
Lopikast (Lopinavir/Ritonavir) should not be administered in the following cases.

Toxic epidermal necrolysis

Stevens-Johnson syndrome

Erythema multiforme

Urticaria

Angioedema

Alternate Brands
The following are some substitutes for Lopikast (Lopinavir/Ritonavir) tablets.

Lopimune

Alltera

Ritocom

Lopikast (Lopinavir/Ritonavir) tablets can cause certain side effects after administration. It is, thus, important to know and discuss the same with the doctor prior to the therapy.

Unusual sweating

Skin rash

Itching

Peripheral neuropathy

Stomach ache

Diarrhea

Headache

Taste change

Blurred vision

Confusion

Weight loss

Nausea

Fever

Chills

Sweating

Mood changes

Dizziness

Indigestion

Constipation

Redness of skin

Note: Contact your health practitioner immediately if the adverse events occur and worsen with time.

Take Lopikast (Lopinavir/Ritonavir) tablets orally with a glass of water at the same time every day. Do not change the dose strength of the regimen unless your health practitioner prescribes it.

Missed Dose
Consult your health practitioner if you miss a dose of Lopikast (Lopinavir/Ritonavir) tablets. Do not initiate any change in the schedule or strength on your own.

Overdose
Seek emergency medical attention from a health practitioner if you experience any symptoms of overdose after administration.

Warnings For Females
Pregnancy

The health practitioner may not prescribe Lopikast (Lopinavir/Ritonavir) tablets during pregnancy due to their influence on the health of the unborn baby.

Breastfeeding

If your health practitioner prescribes Lopikast (Lopinavir/Ritonavir) tablets, make sure to avoid breastfeeding.

Precautions
Contraception

During your treatment with Lopikast (Lopinavir/Ritonavir), make sure to use effective contraceptives to hinder pregnancy or transmission of the virus.

Dose

Do not change the frequency or strength of your prescribed dose of Lopikast (Lopinavir/Ritonavir) unless your health practitioner prescribes it.

Cautions
Alcohol

Lopikast (Lopinavir/Ritonavir) can interact with alcohol and related drinks. This may cause severe effects. However, limited studies are available to justify this.

Driving

Lopikast (Lopinavir/Ritonavir) tablets can cause dizziness or blurred vision after administration. Don’t drive if you do not feel well.

DESCRIPTION

  • Composition : Lopinavir & Ritonavir
  • Manufacturer: Aprazer Healthcare
  • Dosage Form: Tablet

PACKAGE

  • 200 mg
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