• Composition: Lorlatinib
  • Manufacturer: Everest
  • Indication: Lung Cancer
  • Packaging: Tablet 30
  • Dosage Form: Tablet


  • 100mg


Brand name – Lorbrexen

Generic name – Lorlatinib

Manufacture – Everest

Strength – 100mg

Dosage – Tablet

Composition – Lorlatinib

Indication – Lung cancer

Storage – at a cool place

Overview Of Lorbrexen 100mg Tablet

Lorbrexen 100mg tablet is used to treat non-small cell lung cancer. Lorbrexen is used in patients whose tumors are ALK-positive (Anaplastic lymphoma kinase) and detected in FDA-approved tests. Lorbrexen helps in reducing the cancer cells in the patient’s body. This medicine is very effective and the benefits will be seen soon if patients follow the doctor’s prescription strictly. During treatment with this medicine if the patient faces any type of issues after the beginning of treatment rather than regular days inform your doctor.


Lorbrexen 100mg tablet is a third-generation ALK tyrosine kinase inhibitor. It blocks the ALK protein, which is responsible for the growth of cancer cells in the body. In studies, Lorlatinib has shown an effective against a variety of ALK-positive tumors and resists other ALK TKIs. It may take a few weeks or months to show benefits if strictly follow the doctor’s prescription. However, at the beginning of treatment discuss with the doctor all the benefits and risks.

Side Effects Of Lorbrexen 100mg Tablet

Lorbrexen 100mg tablet may give side effects, it is advisable about the symptoms, which are:

  • Diarrhea
  • Back pain
  • Weight gain
  • Constipation
  • Joint pain
  • Nausea
  • Muscle pain
  • Vomiting
  • Tiredness
  • Headache
  • Rash
  • Itching
  • Vision changes
  • Swelling in arm and leg
  • Breathing problem
  • Cough
  • Fever
  • Depression
  • Nightmare
  • Difficulty in sleeping
  • Dizziness
  • Chest pain
  • Mood swing
  • Weakness
  • Tiredness
  • Feel more hungry and thirsty
  • Hearing problem

If patients face these symptoms, then it is advisable to consult the doctor soon. Do not try to ignore these symptoms because they may give severe side effects or it may damage your internal organs.


Lorbrexen is taken in tablet form with or without food one tablet daily or as per the doctor’s prescription. Patients are advised to strictly follow the doctor’s advice to see results soon. Taking this medicine in the wrong way may give you severe side effects that temporarily or permanently damage your organs.

Missed Dose

The patients should not miss any dose. If any doses are missed, do not take the missed dose at the time of the next dose and consult the doctor.


If the patient by mistake has taken an overdose, contact your healthcare provider or doctor and they will provide you medical attention.

Missing or overdosing will impact the overall health of the patients and may also have side effects. So, the patients should follow the prescription of the doctor strictly.


Lorbrexen 100mg tablet may cause reactions in some patients. Therefore, it is advisable to consult with your doctor and get detailed information about this tablet.

The patients should consult with the doctor about the past or current medicines that are taking or had taken whether it is prescribed or non-prescribed, herbal, or vitamins. Lorbrexen may react with those medicines and affect the mechanisms.

Pregnant and breastfeeding should not take this medicine, meet the doctor before taking it.

It may temporarily decrease fertility in men.

At the beginning of treatment inform the doctor about the previous medical conditions or ongoing if there are any such as:

High blood pressure

Irregular heartbeat

High blood sugar level


Cholesterol level