Brand name – Ibruxen
Generic name – Ibrutinib
Manufacturer – Everest
Strength – 140mg
Dosage Form – Capsules
Composition – Ibrutinib
Indication – Leukemia
Storage – at 20° – 25° C
Overview Of Ibruxen 140mg Capsule
Ibruxen 140mg capsule are target therapy medication for the treatment of leukemia. The generic name of this medication is Ibrutinib. Ibruxen is a kinase inhibitor that is used in the treatment of –
- Mantle cell lymphoma
- Waldenstorm’s macroglobulinemia
- Chronic lymphocytic leukemia
- Marginal zone lymphoma
- Chronic graft versus host disease
- Pharmacodynamics
Ibruxen is a Bruton tyrosine kinase inhibitor. BTK is involved in the maturation of the cancerous blood cells. Therefore Ibruxen binding inhibits the maturation of abnormal B-cells also it has antineoplastic properties. So, Ibruxen stops the growth and spreading of abnormal blood cells.
Side Effects Of Ibruxen 140mg Capsule
Swelling of hands and feet
Blurred vision
Trouble in sleeping
Pink eyes
Sores in the mouth and throat
Loss of appetite
Heartburn
Dark colouration in urine
Shortness of breath
Irregular heart rate
Blood in vomit
Weak immune system
Dizziness
Extreme fatigue
Diarrhea
Constipation
Vomiting
Seizures
Increased bruises
DOSAGE
Ibruxen 140mg capsules are prescribed by the doctor hence, it is taken orally once every day and it is advisable to avoid taking Seville oranges and grapefruit with it.
Missed Dose
It is advisable to avoid missing any doses of Ibruxen however if you miss a dose consult your doctor immediately.
Overdose
In case of an overdose of Ibruxen, contact your doctor or any healthcare provider and seek medical attention immediately.
WARNINGS
Ibruxen 140mg can cause an allergic reaction in some patients thus it is necessary to read the complete composition list and consult the doctor in case of any ingredient that induces allergies.
Inform the doctor about all the vitamin supplements, herbal medications, and prescription and non-prescription drugs since they can affect Ibruxen.
It is advisable to avoid pregnancy and breastfeeding during and till one month after the last dose as Ibruxen can harm the fetus.
Avoiding alcohol consumption and operating heavy machinery is not advisable while taking Ibruxen capsules.
Inform the doctor about past medical conditions like liver, kidney disease, hypertension, and high cholesterol.