DAUNOMYCIN

DESCRIPTION

  • Composition: Daunorubicin Hydrochloride
  • Manufacturer: Pfizer
  • Indication: acute lymphocytic leukemia
  • Packaging: Vial
  • Dosage Form: Injection

PACKAGE

    • 20mg

Medicine Details
Brand Name:- Daunomycin

Generic Name:- Daunorubicin Hydrochloride

Manufacturer:- Pfizer

Dosage Form:- Injection

Strength:- 20mg

Composition:- Daunorubicin Hydrochloride

Packaging:- 1vial

Indication:- Kaposi’s Sarcoma, acute lymphocytic Leukemia

Overview
This medication is used to treat a certain type of cancer (Kaposi’s sarcoma). Daunorubicin belongs to the group of antineoplastic (cancer-fighting medicines) known as anthracyclines. This medication works by slowing or stopping the growth of cancer cells. This medicine is given as an infusion into your vein. Do not self-administer this medicine. Take this medicine as prescribed by your medical advisor. Dosage is based on your medical condition and your response to the treatment. Do not take this medicine in the wrong way as it may lead to some severe side effects. Close monitoring of kidney function and the blood cell count is required while receiving this medication. If you experience any symptoms while receiving this medicine, inform your doctor immediately.

Pharmacodynamics Of Daunorubicin
Daunorubicin forms complexes with DNA by intercalation between base pairs. It inhibits the topoisomerase II activity by stabilizing the DNA topoisomerase II complex, preventing the religation portion of the ligation- relegation reaction that topoisomerase II catalyzes. Daunorubicin also inhibits polymerase activity, affects the regulation of gene expression, and produces free radical damage to DNA.

Side Effects Of Daunorubicin
This medicine may cause some major and minor side effects. It requires immediate medical attention otherwise it can also lead to higher risk. Discuss the risks and benefits of this medication with the doctor before starting the treatment.

Common Side Effects

  • Infections
  • Joint pain
  • Nausea
  • Mouth ulcers
  • Abdominal pain
  • Diarrhea
  • Vomiting
  • Shortness of breath
  • Constipation
  • Dizziness
  • Loss of appetite
  • Fatigue
  • Dehydration
  • Fever
  • Decrease in white blood cells and platelets.
  • Unusual bruising
  • Red spots on the skin
  • Seizure
  • Anemia
  • Stomatitis
  • Allergic reaction
  • Irregular heartbeat
  • Back pain
  • Pain at the injection site
  • Swelling of feet and lower legs
  • Painful or difficult urination
  • Hair loss
  • Infections
  • Cough
  • Blood in urine
  • Pale skin

Note- please contact your doctor, if any side effects occur.

Take this injection as prescribed by your doctor. The injection is given as an infusion into your vein by a doctor or nurse. Do not self administer.

Missed Dose
It is advisable not to miss a dose. If you miss an appointment for a scheduled dose of this medicine, contact your doctor immediately.

Overdose
In case of an overdose, the doctor will provide emergency medical treatment.

Usage Of Daunorubicin
Daunorubicin is an anti-cancer medication, which is used to treat a type of cancer that affects the red blood cells, platelets, and white blood cells except for lymphocytes. This medication damages the genetic material DNA of the cancer cells and stops their growth and multiplication. Do not skip or miss the dosing schedule. It is important to take this medicine exactly as prescribed by your medical advisor. This medicine is not recommended in pregnant women. Avoid activities that may increase the risk of infections.

Before starting treatment with Daunorubicin, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.

Contraception

Use effective methods of contraception to prevent pregnancy while taking this medicine.

Children and adolescents

This medicine is not advisable for use in children and adolescents

Warnings For Female

  • Pregnancy

Do not use Daunorubicin if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.

  • Breastfeeding

This medicine is not recommended for breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication.

Precautions

  • Patients with a history of heart disease need close monitoring because this medication can affect your heart.
  • Close monitoring of blood cell count is required. The doctor will not start the treatment if your blood cell count is low.
  • This medicine may increase the risk of toxic effects on the liver and kidneys.
  • Do not receive any vaccines while having treatment with this medicine.
  • Avoid contact with people who have infections.
  • This medication can reduce the number of platelet cells in the blood.

Cautions

  • Not safe for pregnant women.
  • Do not drive or operate heavy machinery.
  • Do not self-administer this medicine.
  • Do not breastfeed while receiving this medication.
  • May decrease blood count

DESCRIPTION

  • Composition: Daunorubicin Hydrochloride
  • Manufacturer: Pfizer
  • Indication: acute lymphocytic leukemia
  • Packaging: Vial
  • Dosage Form: Injection

PACKAGE

    • 20mg
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