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Brand Name:- Sorafenat

Generic Name:- Sorafenib

Manufacturer:- Natco

Dosage Form:- Tablet

Strength:- 200mg

Composition:- Sorafenib

Packaging:- 120 tablets (120 / bottle)

Indication:- Kidney cancer, Liver cancer, and Thyroid cancer

Storage:- Store at room temperature


Sorafenat (Sorafenib 200mg Tablet) is used to treat certain types of cancer (liver cancer, kidney cancer, and thyroid cancer). This tablet belongs to a class of medication known as a tyrosine kinase inhibitor. This medicine helps to stop the growth of cancerous cells. Take this medicine orally. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change or stop the dose without taking suggestions from your doctor. If you experience any symptoms while receiving this medicine, inform your doctor immediately. Your doctor will decide the exact dosage of this medication.

Pharmacodynamics Of Sorafenat (Sorafenib 200mg Tablet)

Sorafenat is a kinase inhibitor that decreases tumor cell proliferation in vitro. Sorafenat inhibited tumor growth of HCC, RCC, and DTC human tumor xenografts in immunocompromised mice. Reductions in tumor angiogenesis were seen in models of HCC and RCC upon Sorafenat treatment, and increases in tumor apoptosis were observed in models of HCC, RCC, and DTC.

After the oral administration, the effect of this medicine can be observed in 3 hours.

Alternate Brands

  • Sorafina
  • Soranib

Side Effects Of Sorafenat (Sorafenib 200mg Tablet)

This medicine may cause some major and minor side effects. It requires immediate medical attention otherwise it can also lead to higher risk. Discuss the risks and benefits of this medication with a medical advisor before starting the treatment.

Common Side Effects 

  • Diarrhea
  • Abdominal pain
  • Fatigue
  • Coughing up blood
  • Bleeding gums
  • Nausea
  • Bloating
  • Difficulty in breathing
  • Irregular heartbeat
  • Pale skin
  • Seizures
  • Sore throat
  • Indigestion
  • Hair loss
  • Numbness
  • Weight loss
  • Dizziness
  • Rash
  • Joint pain
  • Dry mouth
  • Dehydration
  • Anemia
  • Fainting
  • Lightheadedness
  • Muscle cramps
  • Anxiety
  • Itching
  • Vomiting
  • Tiredness
  • Difficulty in swallowing
  • Weakness
  • Chest  pain
  • Chills

Note- Immediately contact your doctor, if any side effects occur


Take this medicine as prescribed by your doctor. Do not chew or crush the tablet. Take this medicine on an empty stomach.

Missed Dose 

  •  It is advisable not to miss a dose. If you miss a scheduled dose of Sorafenat tablet, contact your doctor immediately.


  • In case of an overdose, the doctor will provide emergency medical treatment.

Usage Of Sorafenat (Sorafenib 200mg Tablet)

Sorfenat tablet works by slowing down the growth of cancer cells. Take this medicine orally on an empty stomach once a day. Try not to miss your regular dosing schedule. Take this medicine as prescribed by your medical advisor. Do not crush or chew the tablet. The dose is decided by a medical advisor according to your response to the treatment and your previous medical condition. Regular monitoring of blood pressure is required during treatment with this medicine.  Keep yourself hydrated and maintain good nutrition while taking this medicine.


Before starting treatment with Sorafenat, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.

  •  Contraception
    • Use effective methods of contraception to prevent pregnancy while taking this medicine.
  • Children and adolescents
    • This medicine is not advisable for use in children and adolescents.

Warnings For Female 

  • Pregnancy
    • Sorafenat tablets shouldn’t be used by pregnant women. Sorafenib may cause harm to the baby. It is recommended that this medicine should be avoided during pregnancy.
  • Breastfeeding
    • This medicine is not recommended for breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication.


  • Regular monitoring of blood pressure is required during the treatment with this medicine.
  • This medicine may increase the risk of bleeding.
  • This medicine should be used with caution in patients with low blood glucose levels.
  • Consult a doctor if you are suffering from heart disease.
  • This medication may cause dizziness.
  • The use of this medicine may cause skin reactions.
  • This medicine can reduce the number of white blood cells in the body.
  • This medication may delay wound healing.


  • Do not drive or operate heavy machinery.
  • Do not break, chew, or crush the medicine.
  • Not safe for pregnant women.
  • Do not breastfeed while receiving this medication.
  • May harm liver