• Composition: ledipasvir and sofosbuvir
  • Manufacturer: hetero
  • Indication: Hepatitis
  • Packaging: Bottle
  • Dosage Form: Tablet


  • 90mg
  • 400mg

Brand Name: Ledifos

Generic Name: Sofosbuvir and Ledipasvir

Manufacturer: Hetero

Dosage Form: Tablet

Strength: 90mg/400mg

Composition: Sofosbuvir 400mg + Ledipasvir 90mg

Packaging: 28 tablets per bottle

Indication: Hepatitis C

Storage: Store at room temperature

Ledifos tablet is a combination of two antiviral drugs Sofosbuvir and Ledipasvir. This medicine is used in the treatment of chronic Hepatitis C virus (HCV). It works by blocking the action of a specific protein and preventing its spread in the body. It is advisable not to change or stop the dose without taking suggestions from your doctor. If you experience any symptoms while receiving this medicine, inform your doctor immediately. Do not take this medicine in the wrong way as it may lead to some severe side effects. Avoid the consumption of alcohol during the time of treatment with this medicine.

Pharmacodynamics Of Ledifos
Sofosbuvir is used in combination therapy with Ledipasvir antiviral medicine to treat chronic hepatitis C virus (HCV) infected patients with HCV genotypes 1-6 and to treat HCV. After the oral administration, the effect of this medicine can be observed in 2 to 4 hours.

Usage Of Ledifos
Sofosbuvir and Ledipasvir are antiviral medications that are used in combination to treat chronic (when the infection moves into the long-lasting stage) Hepatitis C virus (HCV). This medicine works by removing the virus from the blood over a period of time. Take this medicine with or without food orally once a day. This medication may take some time to show effect. Do not miss your regular dosing schedule. The recommended dose is decided by a doctor according to your previous medical condition and response to the treatment. Do not chew or break the tablet and swallow the whole tablet with a glass of water.

Side Effects Of Ledifos 90mg/400mg Tablet

This medicine may cause some mild or severe side effects. Discuss the risks and benefits of this medication with the doctor before starting the treatment.

Common Side Effects

  • Diarrhea
  • Nausea
  • Tiredness
  • Difficulty in breathing
  • Cough
  • Loss of appetite
  • Muscle pain
  • Vomiting
  • Abdominal pain
  • Fatigue
  • Anemia
  • Chills
  • Unusual weakness
  • Itching
  • Blurred vision
  • Cramps
  • Allergic reaction
  • Back pain
  • Loss of strength
  • Irregular heartbeat
  • Chest pain
  • Irritability
  • Dizziness
  • Headache
  • Insomnia
  • Pale skin
  • Mouth ulcers

Note- immediate medical attention is required if any side effect occurs

Dosage Of Ledifos 90mg/400mg Tablet

Take this medicine as prescribed by your doctor. Do not skip or miss your dosing schedule. This medicine can be taken with or without food.

Missed Dose Of Ledifos
It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately.

Overdose Of Ledifos
In case of an overdose, the doctor will provide emergency medical treatment.

Warnings Of Ledifos

Before starting treatment with this medication, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.


Use effective methods of contraception to prevent pregnancy while taking this medicine.

Children and adolescents

This medicine is not advisable for use in children and adolescents.

Warnings For Female

  • Pregnancy

Do not use this medicine if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.

  • Breastfeeding

This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication.

Precautions Of Ledifos

  • This medicine is not recommended in patients who have a history of Hepatitis B infection.
  • Close monitoring of kidney function is required.
  • Inform your doctor if you experience any side effects like nausea, fatigue, headache, anemia, and rashes.
  • Regular monitoring of liver function and the amount of hepatitis C virus (HCV) in your body is required.
  • Contact your doctor if you have complications in the liver other than HCV infection.
  • Do not stop taking this medicine without your doctor’s advice.

Cautions Of Ledifos

  • Do not drive or operate heavy machinery.
  • Do not skip the regular dosing schedule.
  • Not safe for pregnant women.
  • Do not breastfeed while receiving this medication.
  • Do not crush or break the tablet.


  • Composition: ledipasvir and sofosbuvir
  • Manufacturer: hetero
  • Indication: Hepatitis
  • Packaging: Bottle
  • Dosage Form: Tablet


  • 90mg
  • 400mg