Brand name – Mydekla
Generic name – Daclatasvir
Manufacturer – Mylan Pharmaceuticals Pvt Ltd
Salt composition – Daclatasvir (60mg)
Storage – Store at room temperature (10-30°C)
Dosage form – Oral (tablet)
Strength – 60 mg
Packaging – Bottle of 28 tablets
Gender – Unisex
Prescription required – Yes
Indication – used in the treatment of chronic Hepatitis C Virus (HCV) infection
Mydekla 60mg tablet is an antiviral medicine. This tablet is used with other medications
in the treatment of chronic (long-lasting) Hepatitis C Virus infection in adults.
Daclatasvir is a direct-acting antiviral (DAA) agent, that works against Hepatitis C Virus
(HCV) and is used for the treatment of chronic HCV genotype 1 and 3 infections. The
active ingredient of the Mydekla 60mg tablet is Daclatasvir.
Daclatasvir is a direct-acting antiviral (DAA) agent. It targets the NS5A and then causes
a fall in serum HCV RNA levels. It works to disrupt HCV replication by specifically
inhibiting the critical functions of an NS5A protein in the replication complex. It is
demonstrated that it causes downregulation of the hyperphosphorylation of NS5A.
When given at three times the maximum recommended dose, it does not prolong the QT
interval. NS5A is a viral nonstructural phosphoprotein. It is part of a functional
replication complex in charge of viral RNA genome amplification on endoplasmic
reticulum membranes. It binds to HCV RNA. To maintain the HCV replication complex is
mediated by the cis-acting function of basally phosphorylated NS5A and the trans-
the acting function of hyperphosphorylated NS5A works to modulate HCV assembly and
infectious particle formation. Daclatasvir disrupts hyperphosphorylated NS5A proteins
and interferes with the function of new HCV replication complexes. Daclatasvir also
blocks both intracellular viral RNA synthesis and virion assembly/secretion in vivo.
Do not administer this medication if you have a known allergy to Daclatasvir or other
ingredients of Mydekla.
● Daclacure 60 mg tablet
● Natdac 60 tablet
● Hepcfix 60 mg tablet
● Hepcdac 60 mg tablet
● Dalsiclear 60 tablet