Brand Name:- Avastin

Generic Name:- Bevacizumab

Manufacturer:- Roche

Dosage form:- Injection

Strength:- 100mg/4ml

Composition:- Bevacizumab

Packaging:- 1vial

Indication:- Colorectal cancer

Storage:- Store in a refrigerator 


Avastin (Bevacizumab  400mg injection) is an anticancer medicine. It is used in the treatment of certain types of cancers such as colorectal, cervical, ovarian, non-small cell lung cancer, kidney cancer, and brain tumors. This medication helps to stop the growth of tumors. This medicine is given in the form of an injection by your doctor or nurse. Your doctor will decide the dosing schedule according to your medical condition and your response to the treatment. Do not take this medicine in the wrong way as it may lead to some severe side effects. Inform your medical advisor if you are using any other medications.

Bevacizumab is an anti-VEGF (Vascular endothelial growth factor) medication, which is beneficial in the treatment of certain types of cancers; it has also been suggested that Bevacizumab is a promising and useful drug to treat patients with severe and critical COVID-19.

Pharmacodynamics Of Avastin (Bevacizumab 400mg Injection)

Avastin binds vascular endothelial growth factor (VEGF)and prevents the interaction of VEGF to its receptors on the surface of endothelial cells. The interaction of VEGF with its receptors leads to endothelial cell proliferation and new blood vessel formation in in-vitro models of angiogenesis.

Advantages Of Avastin (Bevacizumab 400mg Injection) 

  • Avastin injection treats and lowers the risk of developing cancerous cells and colorectal cancer.
  •  This medicine may be given alone or in combination with other medications to treat non-small cell lung cancer.
  • This is an anti-cancer medicine that is used to kill the cancerous cells in cervical cancer.

Substitutes Of Avastin (Bevacizumab Injection)

  • Bevatas
  • Krabeva
  • Advamab
  • Zybev

Side Effects Of Avastin (Bevacizumab 400mg Injection)

This medicine may cause some serious and unwanted side effects. Which requires immediate medical attention otherwise it can also lead to higher risk. Do not forget to discuss the risks and benefits of this medication with your doctor.

Common Side Effects 

  • Bleeding gums
  • Chest pain
  • Sore throat
  • Fever
  • Dizziness
  • Irregular heartbeat
  • Loss of appetite
  • Body pain
  • Runny nose
  • Vomiting
  • Diarrhea
  • Seizures
  • Unusual bleeding
  • High blood pressure
  • Nose bleeds
  • Dry skin
  • Swelling of the feet, fingers, lower legs.
  • Protein in urine
  • Taste change
  • Cough
  • Shortness of breath
  • Fatigue
  • Nasal congestion
  • Pale skin
  • Headache
  • Hypertension
  • Blood clots
  • Note- If any of these symptoms occur, contact your doctor

Dosage Of Bevacizumab 400mg Injection

Take this injection as prescribed by your doctor. Do not take this medicine in the wrong way and make sure to take this injection according to your dosing schedule.

Missed dose 

  • This medication is given by your doctor or nurse. If you miss an appointment for a scheduled dose of this medicine, contact your doctor immediately. 


  • This medication is given by your doctor or nurse. In case of an overdose, your doctor will provide emergency medical treatment.

Usage Of Avastin (Bevacizumab 400mg Injection) 

This is a cancer medicine that interferes with the growth and spread of cancer cells in the body. It is also used to treat cancer of the membrane lining. Bevacizumab 400mg injection is used alone or in combination with other medicines. Take this medicine according to your medical advisor and do not self-administer this injection. Consult your doctor immediately if you experience any symptoms during treatment with this medicine. This medication may take some time to show results. Do not stop taking this medicine unless your medical advisor tells you to do so. Avastin injection is given once every 2 or 3 weeks.


Before starting treatment with Avastin, please tell your doctor about your previous medical history. If you experience any symptoms while receiving this medicine do not ignore those symptoms because it may lead to a higher risk.

  •  Contraception 
    • Use effective methods of contraception to prevent pregnancy while taking this medicine.
  • Children and adolescents 
    • This medicine is not advisable for use in children and adolescents.

Warnings for female 

  • Pregnancy 
    • Avastin shouldn’t be used by women who are pregnant. Atezolizumab may harm the baby. It is recommended that this medication should be avoided during pregnancy.
  • Breastfeeding 
    • This medicine is not recommended for use in breastfeeding women unless it is necessary. Please consult your medical advisor before starting treatment with this medicine.

General Warning And Precaution While Taking Bevacizumab 400mg Injection

  • This medicine may cause dizziness or fainting and it may affect your ability to drive.
  • This medicine may cause severe bleeding disorders and gastrointestinal perforation.
  • This medication may delay wound healing.
  • Close monitoring of heart function is required.
  • The use of this medicine may cause fetal harm.


  • Do not drive or operate heavy machinery.
  • Not safe for pregnant women.
  • Do not self self-administer medicine.
  • Do not breastfeed while taking this medication.