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RIBOCICLIB 200MG TABLET (KRYXANA)
DESCRIPTION
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PACKAGE
Brand Name: Kryxana
Generic Name: Ribociclib
Manufacturer: Novartis
Dosage Form: Tablet
Strength: 200mg
Composition: Ribociclib
Packaging: 21 tablets (21 / strip)
Indication: Breast cancer
Storage: Store at room temperature
Overview
Kryxana (Ribociclib) tablet is used in the treatment of metastatic (cancer that has spread to other parts of the body) breast cancer. It belongs to a group of cancer-fighting medications known as antineoplastics. This tablet works by blocking the action of the kinase protein which is important for the growth and division of cells. Take Kryxana tablet as prescribed by your healthcare provider. Close monitoring of blood cell count is required during treatment with this medicine. The recommended dose of Kryxana tablets is decided by a doctor according to your previous medical condition and response to the treatment.
Pharmacodynamics
Ribociclib is an inhibitor of cyclin-dependent kinase (CDK) 4 and 6. These kinases are activated upon binding to D-cyclins and play a crucial role in signaling pathways which lead to cell cycle progression and cellular proliferation. After the oral administration, the effect of this medicine can be observed in 2 to 4 hours.
Usage
Kryxana tablet is an anti-cancer medication that is used in the treatment of breast cancer. This medicine helps to stop the growth of cancer cells. Take this medicine with or without food orally once a day. Swallow the whole tablet with a glass of water. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately. Avoid the consumption of pomegranate and grapefruit during treatment with this medicine.
Interactions
Kryxana tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
Medicine Interactions
- Clarithromycin
- Alfuzosin
- Dofetilide
- Everolimus
- Halothane
- Levofloxacin
Disease Interaction
- Lung toxicity
Alcohol Interaction
- Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Contraindications
- Do not take this medicine if you are allergic to Ribociclib.
- Kryxana (Ribociclib) medicine is not recommended in patients known to be hypersensitive.
Side Effects
This medicine may cause some side effects. Discuss the risks and benefits of the Kryxana tablets with the doctor before starting the treatment.
Common side effects
- Irregular heartbeat
- Decreased appetite
- Weight gain
- Fainting
- Bloating
- Chills
- Fever
- Pale skin
- Sore throat
- Bleeding
- Seizures
- Vomiting
- Diarrhea
- Chest tightness
- Stomach pain
- Nausea
- Unusual tiredness
- Itching
- Loss of strength
- Changed sense of taste
- Trouble sleeping
- Headache
- Decreased white blood cell count
- Back pain
- Tingling of hands and feet
- Shortness of breath
- Swollen glands
- Coughing up blood
- Unusual weakness
- Nosebleeds
- Bruising
- Allergic reactions
- Severe dizziness
- Sweating
Note – please consult your healthcare provider if any side effects occur
Dosage
Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule.
Missed Dose
- It is advisable not to miss a dose. If you miss a scheduled dose of Kryxana tablet, contact your doctor immediately.
Overdose
- In case of an overdose of Kryxana tablets, the doctor will provide emergency medical treatment
Before starting treatment with Kryxana medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
- Contraception
- Use suitable methods of contraception to prevent pregnancy while taking Kryxana tablets.
- Children and adolescents
- Kryxana tablets are not advisable for use in children under the age of 18.
Warnings For Female
- Pregnancy
- Do not use Kryxana (Ribociclib) if you are planning to become pregnant. Avoid this medication at the time of pregnancy.
- Breastfeeding
- This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with Kryxana medicine.
Precautions
- Kryxana medicine may decrease white blood cells in some patients.
- Close monitoring of liver function is required during treatment with this medicine.
- Inform your doctor if you experience any side effects like – dizziness, nausea, abdominal pain, loss of appetite, and vomiting.
- Do not forget to disclose and discuss your previous history with your healthcare provider.
- Kryxana tablets should be used with caution in patients who have prolonged QT intervals.
Cautions
- Do not drive or operate heavy machinery.
- Do not crush or break the tablet.
- Not safe for pregnant women.
- Do not breastfeed while receiving this medication.
