BORTRAC 2 INJECTION/ VIAL

Brand name – Bortrac 2

Generic name – Bortezomib

Manufacturer – Glenmark

Strength – 2mg

Dosage Form – Injection

Composition – Bortezomib

Indication – Multiple Myeloma

Storage – 20° – 25° C

Overview

Bortrac 2 injection is a targeted therapy that is used in the treatment of multiple myeloma. It is commonly used in patients who have had two unsuccessful previous therapies. The generic name of this medication is Bortezomib and it is a proteasome inhibitor. Bortrac 2mg vial is injected intravenously by a doctor or a trained nurse only.

Pharmacodynamics

Bortrac 2 is a dipeptide boronic acid derivative which functions as a proteasome inhibitor. This medication inhibits the functioning of 26S proteasome which furthermore causes apoptosis in cancerous cells. In addition, it arrests the cell cycle in the middle. Bortrac 2 suppresses the NF – κB signaling pathway which is associated with anti-apoptotic genes. Thus Bortrac 2 suppresses the tumors progressively.