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Brand name – Afanat

Generic name – Afatinib

Manufacturer – Natco

Strength – 40mg/30mg

Dosage Form – Tablets

Composition – Afatinib

Indication – Lung Cancer

Storage – at room temperature

Overview Of Afanat

Afanat 40mg tablets is a chemotherapy medication that is used in the treatment of non-small cell lung cancer. The generic name of this medication is Afatinib. It is a 4-anilinoquinazoline tyrosine kinase inhibitor that showcases antineoplastic properties that is it inhibits the growth of cancerous cells. It is a medication that has to be prescribed by the doctors.


Afanat is the first-line treatment for non-small cell lung cancer. It is a potent and irreversible inhibitor of EGFR. EGFR means epidermal growth factor receptor. When mutations in EGFR arise it consequently leads to uncontrollable growth of the cancerous cells of the lung. Afanat binds to the tyrosine kinase of these growth factors and as a result, blocks their signals. In addition, it stops the autophosphorylation. Therefore this medication stops the uncontrollable cell division and spreading of the cancerous cells.

Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Fever
  • Cough
  • Nose bleeds
  • Dry skin
  • Acne
  • Nose bleeds
  • Weight gain
  • Blisters of skin
  • Loss of appetite
  • Cracked or swollen lips
  • Rashes due to sun exposure
  • Dark coloration of urine
  • Shortness of breath
  • Eye pain
  • Increased bruises
  • Irregular heart rate
  • Nail infection
  • Sensitivity to light
  • Yellowing of skin and eyes
  • Painful urination


The doctor prescribes this medicine hence, it is advisable to follow the prescription. Afanat 40mg tablets or Afanat 30mg tablets are taken orally every day without a meal

Missed dose

It is advisable to avoid missing any doses. In case you miss a dose of Afanat 40mg tablets consult your doctor immediately.


In case of an overdose of Afanat 40mg (30mg) tablets, immediately contact your doctor or any healthcare provider and seek medical attention.


  • Afanat can cause an allergic reaction in some patients. Therefore it is mandatory to gather complete information about the composition. Also, consult the doctor in case of any issues.
  • Inform the doctor about all the vitamin supplements, herbal medications, and prescription and non-prescription drugs.
  • The treatment with Afanat 40mg tablets increases the sensitivity of the skin thus it is advisable to avoid sunlight or cover it completely and  wear a sunscreen
  • Consult the doctor if you are planning a pregnancy as Afanat 30mg can cause harm to the fetus.
  • It is advisable to avoid breastfeeding during the treatment with Afanat tablets.
  • Avoid alcohol consumption while consuming Afanat tablets.
  • Also, operating heavy machinery is not advisable.