SOFOCURE

DESCRIPTION

  • Composition: Sofosbuvir
  • Manufacturer: Emcure
  • Indication: Chronic hepatitis C virus (HCV) infection
  • Packaging: bottle of 28 tablets
  • Dosage Form: Tablet

PACKAGE

  • 400mg

Medicine Details
Brand name – Sofocure
Generic name – Sofosbuvir
Manufacturer – Emcure
Salt composition – Sofosbuvir
Storage – Store at room temperature (10-30°C)
Dosage form – Oral (Tablet)
Strength – 400mg + 100mg
Packaging – Bottle of 28 tablets
Gender – Unisex
Active ingredient – Sofosbuvir
Prescription required – Yes
Indication – Used in the treatment of chronic hepatitis C virus (HCV) infection

Description
Sofocure (sofosbuvir 400mg) is an antiviral medicine. This medicine is used with other medications in the treatment of chronic (long-lasting) Hepatitis C Virus infection in adults. Sofocure should be taken exactly as prescribed by the healthcare provider (in dose and duration). It works by lowering the multiplication of the virus and helps in the removal of virus from the blood over a period of time.

Pharmacodynamics
Sofosbuvir inhibits the hepatitis C NS5B protein. Sofosbuvir appears to have a high barrier to the development of resistance. Sofosbuvir is a prodrug of the Protide type, whereby the active phosphorylated nucleotide is granted with cell permeability and oral bioavailability. By hydrolysis of the carboxylate ester by either of the enzymes cathepsin A or carboxylesterase 1, Sofosbuvir is activated in the liver to the triphosphate GS-461203 followed by cleaving of the phosphoramidate by the enzyme histidine triad nucleotide-binding protein 1 (HINT1), along with repeated phosphorylation. Dephosphorylation then creates the inactive metabolite GS-331077. The half life of Sofosbuvir is 0.4 hours, and the half life of GS-331077 is 27 hours. Following a single 400 mg oral dose of sofosbuvir, 80% is normally excreted in urine, 14% in feces, and 2.5% in expired air recovery.

Ingredients
The active ingredient of Sofocure is Sofosbuvir. The inactive ingredients of Sofocure are colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, mannitol, and microcrystalline cellulose.

Usage Of Medicine
Sofocure (Sofosbuvir) is used with other medications in the treatment of chronic (long-lasting) Hepatitis C Virus infection in adults.

Alternate Brands

  • Resof tablet
  • Sovihep tablet
  • Hepcvir tablet
  • Sofovir tablet
  • Sofab tablet

Side-Effects

Common Side-Effects

  • Tiredness
  • Confusion
  • Dizziness
  • Headache
  • Weakness
  • Joint pain
  • Fever
  • Chills
  • Muscle pain
  • Irritability
  • Skin rash
  • Itching
  • Fatigue
  • insomnia

Serious Side-Effects

  • Chest pain
  • Diarrhea
  • Anemia
  • Fainting
  • Shortness of breath
  • Memory loss

Normal Dose
Take Sofocure (Sofosbuvir 400mg) exactly as your healthcare provider tells you. Do not alter the dose strength. Do not chew, crush or break the tablet. Swallow the tablet as a whole.

Missed Dose
Take the dose as soon as possible, if you miss the dose. However, if it is already the time for the next dose, do not take the missed dose. Do not double up the dose to catch up.

Overdose
Seek emergency medical attention.

  • Avoid consumption of alcohol.
  • If you have liver disease, tell your healthcare provider about the same before taking this medicine.
  • If you have kidney disease, dose alteration may be needed. Therefore, make sure to tell your doctor about the same before taking Sofocure.
  • Tell your healthcare provider about your medical history and the medicines you take already.
  • During pregnancy, it is important to consult a doctor before taking any medicine. Make sure to do so in case of this medicine also.
  • Sofocure 400mg is safe for use during breastfeeding only if prescribed by the healthcare provider.

DESCRIPTION

  • Composition: Sofosbuvir
  • Manufacturer: Emcure
  • Indication: Chronic hepatitis C virus (HCV) infection
  • Packaging: bottle of 28 tablets
  • Dosage Form: Tablet

PACKAGE

  • 400mg
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