LORLATINIB 100MG TABLET (LORBRENA)

LORLATINIB 100MG TABLET (LORBRENA)

DESCRIPTION

PACKAGE

OVERVIEW & USAGE

Brand Name:- Lorbrena

Generic Name:- Lorlatinib

Manufacturer:- Pfizer

Dosage Form:- Tablet

Strength:- 100mg

Composition:- Lorlatinib

Packaging:- 30 tablets

Indication:- Lung cancer

Storage:- Store it at room temperature

Overview Of Lorlatinib 100mg Tablet

Lorbrena (lorlatinib) tablets are used in the treatment of non-small cell lung cancer, which has spread in other areas of the body. This medication works by slowing or stopping the growth of cancer cells. This medicine is used in patients who have a certain type of abnormal anaplastic lymphoma kinase (ALK) gene. Lorlatinib is given when other medicines have stopped working. Your doctor will decide the exact and proper dosing schedule. Do not stop the use of medicine without taking permission from your doctor.

Pharmacodynamics Of Lorbrena (Lorlatinib)

Lorlatinib is a kinase inhibitor that has shown in vitro activity against several genes and protein rearrangements, including ALK, ROS1, TYK1, FER, FPS, TRKA, TRKB, TRKC, FAK, FAK2, and ACK. The gene rearrangement of ALK is a genetic alteration that drives the development of non-small cell lung cancer in several patients. Lorlatinib single oral dose absorbed in 1 to 2 hours.


Side Effects Of Lorbrena (Lorlatinib 100mg Tablet)

This medicine may cause some serious and unwanted side effects. Which requires immediate medical attention otherwise it can also lead to higher risk. Do not forget to discuss the risks and benefits of this medication with your doctor.

Common Side Effects

  • Anxiety
  • Bleeding gums
  • Cough
  • Blurred vision
  • Body ache
  • Fever
  • Sore throat
  • Pale skin
  • Swelling
  • Chest pain
  • Trouble in breathing
  • Back Pain
  • Vomiting
  • Dizziness
  • Nausea
  • Drowsiness
  • Joint pain
  • Headache
  • Weakness
  • Fatigue
  • Weight gain
  • Diarrhea
  • Abdominal pain
  • Slow heartbeat
  • Fainting
  • Trouble in speaking
  • Allergic reaction
  • Difficulty in urination
  • Runny nose
  • Congestion
  • Skin rash
  • Burning and tingling sensations
  • Stiffness

Note- please contact your doctor, if you experience any side effects.


Dosage

Use this medicine as prescribed by your doctor. Do not take this medicine in the wrong way and make sure to take this medication according to your dosing schedule.

Missed Dose 

  • In case you missed a dose, immediately contact your doctor. Do not use extra medicine to double up for the missed dose.

Overdose 

  • Emergency medical treatment is required. Please contact your medical advisor in case of an overdose.

Usage Of Lorbrena (Lorlatinib)

This medicine is used to treat lung cancer. Take this medicine orally with or without food once daily. Try to take this medicine at the same time to get the most benefits of it. This medication helps to stop the growth of cancer cells in the body. Swallow the whole tablet and do not crush or chew the tablet. Take this medicine as directed by your medical advisor. Your dosage is based on your medical condition, age, and response to the treatment. Do not take 2 doses to make up for the missed dose. If you vomit after taking the medicine, do not take another dose.


Warnings

Before starting treatment with the Lorbrena tablet, do not forget to discuss your previous medical history with your doctor.

  •  Contraception
    • Use effective methods of contraception to prevent pregnancy while taking this medicine.
  • Children and adolescents
    • This medicine is not advisable for use in children and adolescents.

Warnings For Female 

  • Pregnancy
    • Lorbrena tablets shouldn’t be used by women who are pregnant. It is recommended that this medication should be avoided during pregnancy.
  • Breastfeeding
    • This medicine is not recommended for use in breastfeeding women unless it is necessary. Please consult your doctor.

General Warning And Precautions 

  • A regular blood test is necessary during treatment with this medicine.
  • Tell your doctor if you have allergies
  • Share your previous medical history with your doctor.
  • Don’t forget to tell your doctor if you ever have an irregular heartbeat, depression, or high cholesterol.
  • Do not breastfeed while taking this medicine.
  • Do not take this medicine if you are pregnant.
  • This medicine may cause eye problems such as – changes in vision, and pain in the eyes.

Cautions

  • Do not crush, chew, or break the medicine.
  • Not safe for pregnant women.
  • Do not drive if you experience any sign of dizziness.
  • Do not take 2 doses at the same time.
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