Overview and Usage

Medicine details

Brand Name:- Crizalk

Generic Name:- Crizotinib

Manufacturer:- Pfizer

Dosage Form:- Capsule

Strength:- 250mg

Composition:- Crizotinib

Packaging :- 60 capsules

Indications :- Lung cancer

Storage conditions:- Store it at room temperature


Crizalk (crizotinib) capsules are used for the treatment of non-small lung cancer, which is a type of cancer that affects the lungs. Crizotinib 250mg Capsule is an anticancer drug that belongs to a category of medicine called protein kinase inhibitors. It acts by inhibiting the action of tyrosine kinase, an enzyme that transmits the growth and spread of cancer cells. Take Crizotinib 250mg Capsule with or without food. Do not try to reduce or increase the dosage form without taking permission from your doctor. Contact your medical advisor if you experience any unusual side effects. Do not stop the use of medicine without asking your doctor.

How Does Crizotinib 250mg Capsule Work? 

A single oral dose, Crizalk is absorbed with a median time to achieve a peak concentration of 4 to 6 hours. Following crizalk twice daily, a steady state was reached within 15 days and remained stable.

Usage Of Crizotinib 250mg Capsule

Crizotinib 250mg Capsule is used for the treatment of metastatic non-small cell lung cancer. Crizalk interferes with the growth of cancer cells which are eventually destroyed by the body. Take Crizotinib 250mg Capsule orally with or without food. The dosage depends upon the age, weight, and medical history of the patients.

Side Effects Of Crizotinib 250mg Capsule

Crizotinib 250mg Capsule may cause some unwanted effects:-

Common Side Effects 

  • Constipation
  • Fatigue
  • Dizziness
  • Headache
  • Fever or chills
  • Taste changes
  • Heartburn
  • Nausea
  • Swelling
  • Diarrhea
  • Cough
  • Chest pain
  • Body ache

Serious Side Effect 

  • Vision problems
  • Bradycardia
  • Shortness of breath
  • Lightheadedness
  • Painful mouth sores
  • Pain in swallow food
  • Bleeding
  • Liver problems

Note- if any of these side effects occur, please contact your doctor.


Crizotinib 250mg Capsule comes in the form of a capsule. Take this medicine orally with or without food or as advised by your doctor.

Missed Dose 

  • In case you missed a dose, immediately contact your doctor.


  • In case of an overdose emergency medical treatment is required.

Warnings Of Crizlak

General Warnings And Precautions 

  • Do not breastfeed while taking Crizotinib 250mg Capsule
  • Avoid drinking grapefruit juice or eating grapefruit.
  • Close monitoring of liver function is required with this medication.
  • Crizotinib 250mg Capsule may decrease heart rate. Regular monitoring of heart rate and blood pressure is required.
  • This medicine may cause visual loss.
  • Try to avoid driving or operating machinery after taking Crizotinib 250mg Capsule.
  • This medicine is not advisable for use in patients with a known allergy to crizotinib.  

Before taking this medication, tell your doctor about your previous medical history 


  • Use effective methods of contraception to prevent pregnancy while taking this medicine. 
  • Children and adolescents 
    • This medicine is not safe for use in children and adolescents.

Warnings for female 

  • Pregnancy 
    •  Crizotinib 250mg Capsules are unsafe to use during pregnancy. Please consult your doctor before taking this medicine.
  • Breastfeeding 
    • This medicine is not recommended during breastfeeding. The risk should be discussed with the doctor before taking this medicine.


  • Do not chew or crush
  • May harm liver
  • Not safe for pregnant women
  • Not safe during breastfeeding
  • May decrease heart rate