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IMATIKAST
DESCRIPTION
- Composition: Imatinib
- Manufacturer: Aprazer Healthcare
- Indication: Blood Cancer
- Packaging: Strip
- Dosage Form: Tablet
PACKAGE
- 400 mg
Brand name: Imatikast
Generic name: Imatinib
Strength: 400mg
Manufacturer: Aprazer
Dosage form: Tablet
Indication: Blood Cancer
Storage: Store at room temperature
Overview
Imatikast contains Imatinib and it is recommended for the treatment of Blood cancer (Chronic myeloid leukemia and Acute lymphocytic leukemia). This cancer-fighting medication belongs to a class of drugs known as tyrosine kinase inhibitors. Imatikast is available in the form of a tablet with a strength of 400mg. Take this medication orally with food as prescribed by your GP (general practitioner).
Pharmacodynamics
Imatinib is a 2-phenylamino pyrimidine derivative and antineoplastic drug used to treat chronic myelogenous leukemia. It inhibits a number of tyrosine kinase enzymes in a specific manner. Chronic myelogenous leukemia is linked to the Philadelphia chromosome, which promotes the BCR-ABL mutation, which is caused by the fusion of two genes, BCR and ABL. BCR-ABL generates a fusion protein that acts as a constitutively active tyrosine kinase and imatinib works to inhibit this constitutive enzymatic activity.
Usage
Imatikast tablet is prescribed by your healthcare professional for use in the treatment of Blood cancer and GIST (gastrointestinal stromal tumor). To take most of the benefit, administer this medication at the same time each day. Do not take Imatikast tablets in the wrong way and the duration of the treatment depends on the response of the patient’s body. For better efficacy complete the dosing schedule as per your healthcare expert guidelines.
Interactions
It is important to know the interactions of Imatikast tablets with other drugs and diseases, before starting therapy with this medicinal formulation.
Medicine Interactions
- Acalabrutinib
- Brigatinib
- Clozapine
- Enzalutamide
- Ibrutinib
- Rifampin
- Rifapentine
Disease Interactions
- Cardiovascular disease
- Fluid retention
- Bone marrow suppression
- Gastrointestinal disorders
- Hepatic impairment
- Hypothyroidism
- Renal impairment
Alcohol Interaction
- Avoid consuming alcohol while receiving treatment with the Imatikast tablet.
Contraindications
- Imatikast tablet is not indicated for use in the below-mentioned cases. Do not use this medication if any of the below-mentioned apply to you:-
- Hypersensitive to the active ingredients present in the medication.
- Allergic to Imatinib.
Atlernate Brand
- Imarech
Severe or moderate side effects may occur during treatment with Imatikast tablets, if side effects last longer than usual inform your healthcare practitioner as soon as possible.
Common Side Effects
- Diarrhea
- Nausea
- Unusual bleeding
- Abdominal pain
- Bloating
- Bloody stool
- Vomiting
- Mouth sores
- Loss of appetite
- Altered sense of taste
- Heartburn and indigestion
- Joint pain
- Stiffness
- Swelling
- Burning or tingling sensation of skin
- Difficulty in falling asleep
- Skin rash
- Hives
- Bruising
- Itching
- Hair loss
- Swelling of the hands, feet, ankle, and lower legs
- Severe breathing difficulty
- Irregular heartbeat
- Presence of blood in cough
- Yellowing of skin and eyes
Note:- It is advisable to contact a healthcare expert if side effects occur.
Take the Imatikast tablet as prescribed by your medical professional. Make sure to take this anti-cancer formulation in the same amount as directed by your physician.
Missed Dose
If you miss a scheduled dose of Imatikast tablet, contact your GP immediately to know the ways of coping with the missed or skipped dose.
Overdose
In case of an overdose, the patient is advised to consult a healthcare practitioner as soon as possible if any unusual symptoms occur.
Warnings And Precautions
Inform your GP (general practitioner) if you have any pre-existing disorder. Check all the possible benefits and risks before starting treatment with the Imatikast tablet.
Warnings For Females
- Pregnancy
Imatikast (Imatinib) tablets are not recommended for use in pregnant women because they may affect the unborn baby.
- Breastfeeding
Do not use the Imatikast (Imatinib) tablet in breastfeeding. Talk to your healthcare provider before starting treatment with Imatikast.
Precautions
- Before starting treatment with an Imatikast (Imatinib) tablet, inform your GP (general practitioner) if you are suffering from a Hepatic disorder.
- If you are allergic to any of the active ingredients present in the Imatikast tablet.
- Do not start your therapy, if you have a pre-existing disorder of congestive heart failure.
- Make sure to disclose your previous and current clinical condition to avoid interactions.
- The use of Imatikast (Imatinib) tablets may cause some severe allergic reactions.
Cautions
- Do not drive or operate heavy machinery
- Do not skip a dose
- Do not overdose
- Do not increase or decrease the dose strength of the Imatikast (Imatinib) tablet
- Do not break or chew the Imatikast tablet
DESCRIPTION
- Composition: Imatinib
- Manufacturer: Aprazer Healthcare
- Indication: Blood Cancer
- Packaging: Strip
- Dosage Form: Tablet
PACKAGE
- 400 mg
