IMATERO

DESCRIPTION

  • Composition: Imatinib mesylate
  • Manufacturer: Hetero
  • Indication: Blood cancer
  • Packaging: Strip
  • Dosage Form: Tablet

PACKAGE

  • 100mg
  • 400mg

Brand Name: Imatero

Generic Name: Imatinib mesylate

Manufacturer: Hetero

Dosage Form: Tablet

Strength: 100mg and 400mg

Composition: Imatinib mesylate

Indication: Blood cancer

Packaging: 10 tablets (10 / strip)

Storage: Store at room temperature

Overview
Imatero (Imatinib mesylate) tablet is used in the treatment of blood cancer (chronic myeloid leukemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor. It belongs to a family of medications known as tyrosine kinase inhibitors. This medicine inhibits the proliferation and induces apoptosis (planned cell death) in BCR-ABL positive cells (cancer cells). It is important to take this medicine as prescribed by your doctor. The recommended dose of Imatib tablet is decided by a doctor according to your previous medical condition and response to the treatment. Do not stop the use of Imatib tablets without consulting with your doctor. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately.

Pharmacodynamics
Imatinib Mesylate is a protein-tyrosine kinase inhibitor that inhibits the BCR-ABL tyrosine kinase, the constitutive abnormal tyrosine kinase created by the Philadelphia chromosome abnormality in CML. It inhibits proliferation and induces apoptosis in BCR-ABL positive cell lines as well as fresh leukemic cells from Philadelphia chromosome-positive chronic myeloid leukemia.

Interactions
Imatero tablets can interact with other medications and it may increase the risk for side effects.

Don’t forget to disclose and discuss your previous medical history with the doctor.

Medicine Interactions
● Colchicine

● Warfarin

● Pimozide

● Etanercept

● Apalutamide

● Mitotane

● Baricitinib

Disease Interactions
● Fluid retention

● Kidney impairment

● Cardiovascular disease

● Liver impairment

● Bone marrow suppression

Alcohol Interaction
● Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.

Contraindications
● Do not take this medicine if you are allergic to Imatinib mesylate.

● Imatero (Imatinib mesylate) medicine is not recommended in patients known to be hypersensitive.

This medicine may cause some common and serious side effects. Discuss the risks and benefits of the Imatero tablets with the doctor before starting the treatment.

Common Side Effects

● Abdominal pain

● Joint pain

● Headache

● Weight gain

● Insomnia

● Vomiting

● Muscle pain

● Heartburn

● Indigestion

● Constipation

● Blurred vision

● Indigestion

● Dizziness

● Weight loss

● Diarrhea

● Nausea

● Itching

● Joint pain

● Seizures

● Anxiety

 

Serious Side Effects

● Swelling of the hands and feet

● Bloating

● Presence of blood in cough

● Fatigue

● Difficulty in breathing

● Pale skin

● Irregular heartbeat

● Unusual bleeding

● Bloody stool

● Swelling around the eyes

Note – Immediately contact your doctor or medical practitioner if any side effects occur.

Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule.

Missed Dose
● It is advisable not to miss a dose. If you miss a scheduled dose of Imatero tablets, contact your doctor immediately.

Overdose
● In case of an overdose of Imatero tablets, the doctor will provide emergency medical treatment.

Usage
Imatero medicine is also used in the treatment of certain types of cancer of the blood cells, stomach, and intestine. It helps to prevent the growth of cancer cells. Do not take this medicine on an empty stomach. While having treatment with this medicine keep yourself hydrated and maintain good nutrition. Do not take this medicine in the wrong way as it may lead to some severe side effects. Avoid the consumption of alcohol because it may increase the risk of dizziness. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor.

Before starting treatment with Imatero medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.

● Contraception

○ Use suitable methods of contraception to prevent pregnancy while taking this medicine.

● Children and adolescents

○ Imatero tablets are advisable for use in children and adolescents with CML.

Warnings For Female

● Pregnancy

○ Do not use Imatero medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.

● Breastfeeding

○ This medicine is not recommended for breastfeeding unless it is required. Please consult with your doctor before starting treatment with this medication.

Precautions

● This medicine should be used with caution in patients who are suffering from heart disease.

● In children, close monitoring of growth parameters is required during treatment with this medicine.

● Avoid contact with people who have infections.

● Inform your doctor if you experience any side effects like – anxiety, nausea, abdominal pain, difficulty in breathing, irregular heartbeat, and vomiting.

● Close monitoring of thyroid hormones is required in patients suffering from hypothyroidism.

● Imatero tablets may interact with other medications and cause some severe side effects.

Cautions

● Do not drive or operate heavy machinery.

● Do not crush or break the tablet.

● Not safe for pregnant women.

● Do not breastfeed while receiving this medication.

Substitutes

● Imat

● Imatib

● Levin

● Cadinib

DESCRIPTION

  • Composition: Imatinib mesylate
  • Manufacturer: Hetero
  • Indication: Blood cancer
  • Packaging: Strip
  • Dosage Form: Tablet

PACKAGE

  • 100mg
  • 400mg
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