Overview and Usage

Brand name- Gefitero

Generics- Gefitinib

Manufacturer- Hetro healthcare ltd.

Dosage form- Tablet

Route of Administration- oral

Strength- 250mg

Composition- Gefitinib

Packaging- Strip

Indication- non-small cell lung cancer (NSCLC).

Storage- Store at room temperature (10-30°C)

Class of drug- Anti-Neoplastics

Mechanism Of Action

It works by blocking the action of abnormal protein that signals cancer cells to multiply. This in turn helps to slow or inhibit the spread of cancer cells

Side effects-

The most common side effects of gefitero include nausea, rash, vomiting and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult the doctor if it happens. It makes the patient sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out.


It is the study of drug effects and what the medicine does to the body

It inhibits the intracellular phosphorylation of tyrosine kinase associated with epidermal growth factor (EGFR).


Study of what body does to the medicine.Gefitinib is absorbed slowly after oral administration as it has bioavailability of 60%. Elimination is through metabolism (primarily CYP 3A4) and excretion in feces.

Bioavailability Rate

Gefitero is slowly absorbed, with peak plasma levels in 3-7 hours after dosing and mean oral bioavailability of 60%

Shelf Life

Shelf life is the time period over which the concentration of the active medicinal ingredient in the formulation lowers by 10 percent from its value at time of manufacture.
Its shelf life is 26 months

Side Effects


Consult your doctor before taking this medicine, if you:

  • Experience unexplained shortness of breath, cough, and fever that comes on suddenly. These could be symptoms of a serious lung condition.
  • Have severe or continuing diarrhea that lasts up to 14 days.
  • Experiencing adverse skin reactions like blistering, peeling, or loosening of the skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin

Side Effects

Common Side Effects

  • Diarrhea
  • Fever
  • Allergic skin reaction
  • Nausea and Vomiting
  • Increase in liver enzyme levels
  • Eye irritation
  • Difficulty in breathing
  • Abdominal pain
  • Sore throat
  • Redness around fingernails

Serious Side Effects

Unusual bleeding (in cough and urine),eye irritation or pain, or swelling of the ankles or feet


Missed Dose

If patient miss a dose of medicine, skip it and continue with the normal schedule. No need to double the dose


Get the emergency medical treatment and contact your physician


Which disease area
non-small cell lung cancer (NSCLC)
Precaution Usage
Which disease area
non-small cell lung cancer (NSCLC)


General warning and precautions

  • Do not take antacids (to reduce the acid level of your stomach) 2 hours before or 1 hour after administering gefitero.
  • Diarrhea can occur as a side effect. Drink plenty of fluids and inform the doctor in case it doesn’t stop or there is blood in stools.


  • It is usually taken on an empty stomach once a day, at least 1 hour before or 2 hours after eating a meal or snack. Take gefitero at around the same time every day.


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  • Geftinat 250Mg Tablet-  Natco Pharma Ltd
  • Geffon 250Mg Tablet-  Zydus Cadila
  • Chemogef 250Mg Tablet- Neon Laboratories Ltd
  • Geftistar 250mg Tablet-  Lupin Ltd

Alternate Brands

  • Debrit 250 mg Tablet – Pfizer Ltd.
  • Gefitrust 250 mg Tablet – Panacea Biotec Ltd.
  • Geftinat 250 mg Tablet – Natco Pharma Ltd.
  • Geftistar 250 mg Tablet- Lupin Ltd.
  • Grexam 250 mg Tablet- Ranbaxy Laboratories Ltd.