ERIBULIN MESYLATE 0.44MG/ML INJECTION (HALAVEN)

ERIBULIN MESYLATE 0.44MG/ML INJECTION (HALAVEN)

DESCRIPTION

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PACKAGE

Medicine Details

Brand Name: Halaven

Generic Name: Eribulin mesylate

Manufacturer: Eisai Pharmaceuticals India Pvt Ltd

Dosage Form: Injection

Strength: 1mg/2ml

Composition: Eribulin mesylate

Packaging: 1vial

Indication: Breast cancer

Storage: Store at room temperature

Overview

Halaven (Eribulin mesylate) injection is used for the treatment of metastatic breast cancer (cancer that has spread to other parts of the body). This medicine belongs to a class of medications antineoplastic. It works by interfering with the microtubule structures which helps the cancer cells to divide and multiply.  It is important to take a Halaven injection as prescribed by your doctor. The recommended dose of Epitero injection is decided by a doctor according to your previous medical condition and response to the treatment. This medicine is given as an infusion into your vein. Do not self-administer this medicine.

Pharmacodynamics

Halaven 1mg/2ml treatment of human breast cancer cells caused changes in morphology and gene expression as well as decreased migration and invasiveness in vitro. It inhibits the growth phase of microtubules without affecting the shortening phase and sequesters tubulin into nonproductive aggregates.

Usage

This medicine is used when breast cancer has spread to other parts of the body. Halaven injection helps to stop the growth of cancerous cells and also prevents the multiplication of cancerous cells. Do not take this medicine in the wrong way as it may lead to some severe side effects. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately. It is advisable not to change or stop the dose without taking suggestions from your doctor. This medicine increases the risk of dizziness. Avoid activities that require more concentration. This injection affects your immune system and may increase the risk of getting infections or bleeding more easily.

​Interactions

Halaven injection can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.

Medicine Interactions

  • Moxifloxacin
  • Adalimumab
  • Lefamulin
  • Siponimod
  • Etanercept

Disease Interactions

  • Infections
  • Renal impairment
  • Hepatic impairment

Alcohol Interaction

  • Interaction with alcohol is unknown. Please consult your doctor while having treatment with this medicine.

Contraindications

  • Do not take this medicine if you are allergic to Eribulin mesylate.
  • Halaven injection is not recommended in patients known to be hypersensitive.

 

Side Effects

This medicine may cause some common side effects. Discuss the risks and benefits of the Halaven injection with the doctor before starting the treatment.

Common Side Effects

  • Anemia
  • Weakness
  • Hair loss
  • Constipation
  • Fatigue
  • Irregular heartbeat
  • Dizziness
  • Decrease white blood cell count
  • Loss of strength
  • Fainting
  • Weight loss
  • Bloating
  • Sore throat
  • Headache
  • Dry mouth
  • Runny nose
  • Muscle stiffness
  • Back pain
  • Indigestion
  • Diarrhea
  • Rash
  • Loss of appetite
  • Tingling and numbness of feet and hand
  • Cough
  • Pale skin
  • Unusual bleeding
  • Nasal congestion
  • Decreased urination
  • Anxiety
  • Change of taste
  • Shortness of breath
  • Inflammation
  • Dehydration
  • Fever
  • Vomiting

Note –  Contact your medical practitioner if any side effects occur.

Dosage

Take this injection as prescribed by your doctor. The injection is given as an infusion into your vein by a doctor or nurse. Do not self-administer.

Missed Dose

  • It is advisable not to miss a dose. If you miss an appointment for a scheduled dose of Halaven injection, contact your doctor immediately.

Overdose

  • In case of an overdose of Halaven injection, the doctor will provide emergency medical treatment.

 

Warnings

Before starting treatment with Halaven medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.

  •  Contraception
  • Use suitable methods of contraception to prevent pregnancy while taking this medicine.
  • Children and adolescents
  •  Halaven injection is not advisable for use in children and adolescents.

Warnings For Female

  • Pregnancy
  • Do not use Halaven medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.
  • Breastfeeding
  • This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with this medication.

Precautions

  • This medicine may cause prolongation of the QT interval.
  • Halaven injection may decrease white blood cells and increase the risk of infections in patients.
  • Inform your doctor if you experience any side effects like – anemia, infection, nausea, unusual weakness, muscle pain, fever, and bleeding.
  • Do not skip the scheduled dose of this medicine.
  • Close monitoring of blood cell counts and electrolyte levels is required during treatment with this medicine.
  • Avoid contact with people who have infections.

Cautions

  • Do not self-administer.
  • Do not drive or operate heavy machinery.
  • Not safe for pregnant women.
  • Do not breastfeed while receiving this medication.
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