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GEFITINIB 250MG TABLET (GEFTINAT) UP TO 35% OFF
DESCRIPTION
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PACKAGE
Overview and Usage
Brand name- Geftinat
Generics- Gefitinib
Manufacturer- NATCO Pharma Ltd.
Dosage form- Tablet
Route of Administration- oral
Strength- 250mg
Composition- Gefitinib
Packaging- Bottle
Indication- non-small cell lung cancer (NSCLC).
Storage- Store at room temperature (10-30°C)
Class of drug- Anti-Neoplastics
Mechanism Of Action
It works by blocking the action of abnormal protein that signals cancer cells to multiply. This in turn helps to slow or inhibit the spread of cancer cells
Side effects-
The most common side effects of geftinat include nausea, rash, vomiting, and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult the doctor if it happens. It makes the patient sensitive to sunlight, hence wear protective clothing or use sunscreen while going out.
Pharmacodynamics
It is the study of drug effects and what the medicine does to the body
It inhibits the intracellular phosphorylation of tyrosine kinase associated with epidermal growth factor (EGFR).
Pharmacokinetics
Study of what the body does to the medicine. Geftinat is absorbed slowly after oral administration as it has a bioavailability of 60%. Elimination is through metabolism (primarily CYP 3A4) and excretion in feces.
Bioavailability Rate
Geftinat is slowly absorbed, with peak plasma levels in 3-7 hours after dosing and mean oral bioavailability of 60%
Shelf Life
Shelf life is the time over which the concentration of the active medicinal ingredient in the formulation lowers by 10 percent from its value at the time of manufacture.
Its shelf life is 26 months
Usage
Which disease area
non-small cell lung cancer (NSCLC)
Substitutes
GEFIMIPSA 250MG CAPSULE- Ark Life Sciences Pvt Ltd
Geficad 250mg Tablet- Cadila Pharmaceuticals Ltd
Geffon 250Mg Tablet- Zydus Cadila
Chemogef 250Mg Tablet- Neon Laboratories Ltd
Geftistar 250mg Tablet- Lupin Ltd
Alternate Brands
Gefticip 250 mg Tablet (CIPLA Ltd.)
Geftifos 250 mg Tablet (Torrent Pharmaceuticals Ltd.)
Zefotib 250 mg Tablet (Alkem Laboratories Ltd.)
Zufinib 250 mg Tablet (Zuventus Healthcare Ltd.)
Precaution
Consult your doctor before taking this medicine, if you:
Experience unexplained shortness of breath, cough, and fever that comes on suddenly. These could be symptoms of a serious lung condition.
Have severe or continuing diarrhea that lasts up to 14 days.
Experiencing Adverse Skin Reactions Like Blistering, Peeling, Or Loosening Of The Skin, Red Skin Lesions, Severe Acne Or Skin Rash, Sores Or Ulcers On The Skin
Side Effects
Common Side Effects
- Diarrhea
- Fever
- Allergic skin reaction
- Nausea and Vomiting
- Increase in liver enzyme levels
- Eye irritation
- Difficulty in breathing
- Abdominal pain
- Sore throat
- Redness around fingernails
Serious Side Effects
Unusual bleeding (in cough and urine), eye irritation or pain, or swelling of the ankles or feet
Dosage
Missed Dose
If the patient misses a dose of medicine, skip it and continue with the normal schedule. No need to double the dose
Overdose
Get the emergency medical treatment and contact your physician.
Warnings
General Warning And Precautions
Do not take antacids (to reduce the acid level of your stomach) 2 hours before or 1 hour after administering geftinat.
Diarrhea can occur as a side effect. Drink plenty of fluids and inform the doctor in case it doesn’t stop or there is blood in stools.
Cautions
It is usually taken on an empty stomach once a day, at least 1 hour before or 2 hours after eating a meal or snack. Take geftinat at around the same time every day.
